Common Drugs with Effective Off-Label Uses

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Off-label uses of drugs in children.

As we approach the new millennium, very little has changed regarding the labeling of prescription drugs for use in infants and children. Along with pregnant women, infants and children remain therapeutic orphans. This condition is understandable because there are very few therapeutic indications that are unique to this patient population and the absolute quantities of drugs required by these pa...

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off-label and off-nccn guidelines uses of antineoplastic drugs in china.

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Off-Label and Off-NCCN Guidelines Uses of Antineoplastic Drugs in China

BACKGROUND To evaluate off-label and off-NCCN guidelines uses of antineoplastic drugs in a major Chinese hospital. METHODS Totally 1122 patients were selected from July to December 2011. Then, the off-label and off-NCCN guidelines uses of antineoplastic drugs were analyzed. RESULTS In 798 of 1122 patients (71.12%), drugs were used for off-label. In 317 of 1122 patients (28.25%), the drugs w...

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Chelation Therapy for Off-Label Uses

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Promotion of Drugs for Off-label Uses: The US Food and Drug Administration at a Crossroads.

Since 1962, the US Food and Drug Administration (FDA) has required companies to establish, with adequate and well-controlled clinical trials, a drug’s safety and efficacy for each intended use and has prohibited the “offlabel” promotion of drugs. For companies to market an approved medicine for new indications, they must first conduct trials and submit data to establish safety and efficacy, as ...

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ژورنال

عنوان ژورنال: Journal of Pharmaceutical Research International

سال: 2020

ISSN: 2456-9119

DOI: 10.9734/jpri/2020/v32i1030490